.406 Ventures

Q: When was .406 Ventures last fund created?

.406 Ventures last fund was created/launched in 2024-10-14.

General contacts

Investor type

Founded

2006

AUM

$1 400 M

Location

Boston, Massachusetts, United States

Investment Ticket

$1-5 m

Investment Stage

Series B Series A Seed Pre-seed Late Stage (Series C+)

Region of investment

North America Europe

Investor profile last updated: 13 August, 2026

Profile

.406 Ventures is a venture capital firm based in Boston, Massachusetts, founded in 2006. The firm was established with a focus on partnering with early-stage companies that have the potential to become industry leaders. The team at .406 Ventures is composed of experienced professionals who emphasize building strong relationships with founders to help transform their startups into successful enterprises. What sets them apart is their commitment to providing more than just financial support, offering domain-specific knowledge and networks to aid in the growth of their portfolio companies.

The firm primarily invests in the sectors of healthcare, data and AI, and cybersecurity. They focus on early-stage investments and support companies through subsequent funding rounds. .406 Ventures mainly partners with founders in North America. The firm manages several funds, including .406 Ventures Fund V with $265 million, Fund IV with $294 million, and Fund III with $217 million, among others.

Notable investments by .406 Ventures include Able - supply chain tracking, Carbon Black - cybersecurity, CloudHealth - cloud service management, Redox - healthcare data integration, and Corvus - cyber insurance. These investments reflect the firm's strategy of leveraging industry expertise to support and grow its portfolio companies.

Industry

Cybersecurity Cloud Energy MedTech AI Telecommunications Sports/SportsTech Software Security Real Estate Other Media and Entertainment Marketing and Advertising Healthcare Services Fintech Financial Services Fashion/Beauty Digital HealthTech Business Services (B2B) Technology SaaS CleanTech

.406 Ventures Funds

Name	Type	Industry	Stage	Region	Size	AUM	Launch date
.406 Ventures Fund V	Venture Capital (VC)	Healthcare Services AI Cybersecurity	Seed Series A	North America	$1-5 m	$265 M	October 2024
.406 Ventures Fund III	Venture Capital (VC)	Business Services (B2B) Fintech Healthcare Services AI Technology Cybersecurity	Series A	North America	$5-10 m	$217 M	July 2015
.406 Ventures Fund II	Venture Capital (VC)	AI Technology	Pre-seed Seed	North America	$5-10 m	$175 M	December 2012
.406 Ventures Fund IV	Venture Capital (VC)	Software AI Technology Cybersecurity HealthTech	Pre-seed Seed	North America	$5-10 m	$294 M	December 2019
.406 Ventures 2016 Opportunities Fund, L.P.	Venture Capital (VC)	Financial Services Fintech Healthcare Services Marketing and Advertising Media and Entertainment SaaS Security Software Energy CleanTech HealthTech	Pre-seed Seed	North America Europe Middle East	$5-10 m	$80 M	December 2016
.406 Ventures 2016 Opportunities Fund II	Venture Capital (VC)	Financial Services Fintech Healthcare Services Marketing and Advertising Media and Entertainment SaaS Security Software Energy CleanTech HealthTech	Pre-seed Seed	North America	$5-10 m	—	December 2019

Contacts

Name

Title

Social Networks

Maria Cirino Founding Managing Partner

Founding Managing Partner

m•••@•••

Liam Donohue Founding Partner

Founding Partner

l•••@•••

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Investment-team contacts for .406 Ventures — including verified work emails and LinkedIn profiles — are available to Private Equity List subscribers.
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FAQs about .406 Ventures

Is .406 Ventures a venture capital or private equity firm?

.406 Ventures is a venture capital firm. It backs companies at Series B, Series A, Seed, Pre-seed and Late Stage (Series C+), writing tickets of $1-5 m.

Where is .406 Ventures located?

.406 Ventures is located in Boston, Massachusetts, United States.

When was .406 Ventures founded?

.406 Ventures was founded in 2006.

What sectors and industries does .406 Ventures invest in?

.406 Ventures invests in companies and startups in Cybersecurity, Cloud, Energy, MedTech, AI, Telecommunications, Sports/SportsTech, Software, Security, Real Estate, Other, Media and Entertainment, Marketing and Advertising, Healthcare Services, Fintech, Financial Services, Fashion/Beauty, Digital, HealthTech, Business Services (B2B), Technology, SaaS, CleanTech.

What is .406 Ventures geographical focus of investments?

.406 Ventures invests in companies and startups in North America, Europe.

At what stages of companies and startups does .406 Ventures typically invest in?

.406 Ventures invests in companies and startups at Series B, Series A, Seed, Pre-seed, Late Stage (Series C+).

What is the usual amount of .406 Ventures investment?

.406 Ventures usually invests $1-5 m on average.

What is the amount of assets of under management (AUM) for .406 Ventures?

.406 Ventures has around $1 400m assets under management.

When was .406 Ventures last fund created?

.406 Ventures last fund was created/launched in 2024-10-14

What are the contacts of .406 Ventures?

.406 Ventures can be reached through its website 406ventures.com, its LinkedIn page and its X account. Its general enquiries address is [email protected]. Cold-mailing a general inbox rarely reaches a partner, so Private Equity List also lists the investment-team contacts for .406 Ventures — names, roles, verified work emails and LinkedIn profiles — available on a Pro plan from $129/month (see pricing). Contacts are sourced from the firm's website and LinkedIn and re-verified on a rolling cycle. Spot a stale contact, or none at all? Report it — we re-run that firm within 48h and get back to you.

Can I access .406 Ventures data via API or MCP?

Yes. Every field on this page — profile, funds, investment criteria, portfolio and investment-team contacts — is available programmatically through the Private Equity List REST API and MCP server, so AI assistants such as Claude and ChatGPT can query .406 Ventures directly instead of scraping this page. One subscription covers both the web app and machine access — see API & MCP.

When was the .406 Ventures profile last updated?

Private Equity List re-verifies investor profiles on a rolling cycle, pulling from the firm's own website and LinkedIn rather than a one-off import. This profile was last updated on 13 August, 2026. Something out of date here? Report it — we re-run that firm within 48h and get back to you.