SR One

General contacts
Investor type

VC / CVC

Founded

1985

AUM

$1 600 M

Location

Redwood City, California, United States

Investment Ticket

$10-50 m

Investment Stage

Series B Series A Seed Late Stage (Series C+)

Region of investment

North America Europe
Investor profile last updated: 16 August, 2026

Profile

SR One is a venture capital firm with offices in Redwood City, California, and London, United Kingdom. The firm is led by Founder & CEO Simeon J. George, MD, and operates with a team experienced in healthcare and life sciences sectors. They are known for their transatlantic approach, leveraging continuity of experience to accelerate value creation across their investments.

SR One predominantly invests in the life sciences sector, with a focus on biotechnology, pharmaceuticals, and healthtech. Their investment sizes typically range from $10-50 million, targeting Series A through late-stage rounds primarily in North America and Europe.

Notable portfolio companies include Avalyn Pharma - focused on respiratory therapeutics, BioTheryX - working on protein modulation therapies, Palleon Pharmaceuticals - developing immune-oncology treatments, Poplar Therapeutics - specializing in immunotherapy, and Rezo Therapeutics - focusing on precision oncology.

Industry

HealthTech Software Biotechnology Healthcare Services Other Pharmaceuticals Medical Devices Life Sciences Technology

SR One Funds

Name Type
Questionare
Industry
Questionare
Stage
Questionare
Region 		Size AUM Launch date
SR One Fund I
Venture Capital (VC)
Biotechnology
Healthcare Services
Medical Devices
Pharmaceuticals
Life Sciences
Seed
Series A
Series B
North America
Europe
$5-10 m
$500 M
November 2021
SR One Fund II
Venture Capital (VC)
Biotechnology
Healthcare Services
Medical Devices
Pharmaceuticals
Technology
Life Sciences
Seed
Series A
Series B
North America
Europe
$5-10 m
$600 M
March 2023

Contacts

Name
Title
Email
Social Networks
avatar
Lynne Murray Venture Partner
Venture Partner
l•••@•••
LinkedIn
avatar
Amit Shah Principal
Principal
a•••@•••
LinkedIn
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Investment-team contacts for SR One — including verified work emails and LinkedIn profiles — are available to Private Equity List subscribers.
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FAQs about SR One

SR One is a venture capital firm that also operates as a corporate VC (CVC). It backs companies at Series B, Series A, Seed and Late Stage (Series C+), writing tickets of $10-50 m.
SR One is located in Redwood City, California, United States.
SR One was founded in 1985.
SR One invests in companies and startups in HealthTech, Software, Biotechnology, Healthcare Services, Other, Pharmaceuticals, Medical Devices, Life Sciences, Technology.
SR One invests in companies and startups in North America, Europe.
SR One invests in companies and startups at Series B, Series A, Seed, Late Stage (Series C+).
SR One usually invests $10-50 m on average.
SR One has around $1 600m assets under management.
SR One last fund was created/launched in 2023-03-27
SR One can be reached through its website srone.com and its LinkedIn page. Its general enquiries address is [email protected]. Cold-mailing a general inbox rarely reaches a partner, so Private Equity List also lists the investment-team contacts for SR One — names, roles, verified work emails and LinkedIn profiles — available on a Pro plan from $129/month (see pricing). Contacts are sourced from the firm's website and LinkedIn and re-verified on a rolling cycle. Spot a stale contact, or none at all? Report it — we re-run that firm within 48h and get back to you.
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Private Equity List re-verifies investor profiles on a rolling cycle, pulling from the firm's own website and LinkedIn rather than a one-off import. This profile was last updated on 16 August, 2026. Something out of date here? Report it — we re-run that firm within 48h and get back to you.