Twine Ventures

General contacts
Investor type

VC

Founded

2021

AUM

-

Location

San Francisco, California, United States

Investment Ticket

-

Investment Stage

Seed Series A

Region of investment

North America

ESG Focus

Women People of color and other minorities
Investor profile last updated: 16 August, 2026

Profile

Twine Ventures is a venture capital firm based in San Francisco, California, founded in 2021 by Leshika Samarasinghe and Ethan Yeh. Leshika has a background in early product teams at Google and was a founding member of ARPA-E, while Ethan was a former Head of Data Science at Stripe and director at Twitter. The firm is known for its hands-on approach, partnering with founders from the earliest stages to drive competitive Series A fundraises.

Twine Ventures focuses on sectors such as healthcare, climate, and financial empowerment, investing in interdisciplinary teams that leverage data and AI. They typically write first checks ranging from $250K to $1M, targeting seed and Series A stages. The firm invests primarily in the USA and has a portfolio that includes companies like Airship, Alaffia, and Alchemy. Twine Ventures does not lead rounds but provides co-investment access and support for women and BIPOC founders.

Notable investments by Twine Ventures include Airship - sales enablement software for HVAC professionals, Alaffia - AI-based payment integrity for healthcare, Alchemy - tech-enabled pharmacy for underserved populations, Alden - staffing optimization for home care, and Alpha Grid - pricing intelligence for EV charging infrastructure.

Industry

Fintech Healthcare Services Industrial AI ClimateTech

Contacts

Name
Title
Email
Social Networks
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Leshika Samarasinghe Founder & Managing Partner
Founder & Managing Partner
l•••@•••
LinkedIn
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Ethan Yeh, PhD managing Partner
managing Partner
e•••@•••
LinkedIn
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FAQs about Twine Ventures

Twine Ventures is a venture capital firm. It backs companies at Seed and Series A.
Twine Ventures is located in San Francisco, California, United States.
Twine Ventures was founded in 2021.
Twine Ventures invests in companies and startups in Fintech, Healthcare Services, Industrial, AI, ClimateTech.
Twine Ventures invests in companies and startups in North America.
Twine Ventures invests in companies and startups at Seed, Series A.
Twine Ventures invests and supports Women, People of color and other minorities startups and founders.
Twine Ventures can be reached through its website twineventures.com and its LinkedIn page. Its general enquiries address is [email protected]. Cold-mailing a general inbox rarely reaches a partner, so Private Equity List also lists the investment-team contacts for Twine Ventures — names, roles, verified work emails and LinkedIn profiles — available on a Pro plan from $129/month (see pricing). Contacts are sourced from the firm's website and LinkedIn and re-verified on a rolling cycle. Spot a stale contact, or none at all? Report it — we re-run that firm within 48h and get back to you.
Yes. Every field on this page — profile, funds, investment criteria, portfolio and investment-team contacts — is available programmatically through the Private Equity List REST API and MCP server, so AI assistants such as Claude and ChatGPT can query Twine Ventures directly instead of scraping this page. One subscription covers both the web app and machine access — see API & MCP.
Private Equity List re-verifies investor profiles on a rolling cycle, pulling from the firm's own website and LinkedIn rather than a one-off import. This profile was last updated on 16 August, 2026. Something out of date here? Report it — we re-run that firm within 48h and get back to you.